San Francisco 49ers Defeat Los Angeles Rams 27-7 Amid Multiple Injuries

Jake Tonges had become a significant contributor during George Kittle’s absence in 2025, catching 29 of 40 targets for 269 yards and three touchdowns over six games. He also ran 200 routes during that stretch before signing a two-year, $8 million offseason contract.
De’Zhaun Stribling was selected 33rd overall in the 2026 NFL Draft and entered the opener after an encouraging preseason in which he caught 11 passes for 109 yards in two games.
Stribling’s ankle problem initially appeared to be a non-contact injury: he limped to the medical tent during San Francisco’s second drive, returned in the second quarter and then needed help leaving after another play involving Rams cornerback Trent McDuffie.
Stribling began his football career as a quarterback before switching to wide receiver in seventh grade. He played 56 games with 55 starts at Mississippi and graduated from Oklahoma State with a degree in university studies.
San Francisco’s receiving corps was already built around Mike Evans and Deebo Samuel, with Stribling, Demarcus Robinson and Jacob Cowing providing depth; Stribling’s departure therefore further reduced the options available around quarterback Brock Purdy.
The San Francisco 49ers dominated the Los Angeles Rams 27-7 in their season opener in Melbourne, Australia, but paid a steep price in injuries. Rookie wide receiver De'Zhaun Stribling, the 33rd overall draft pick, was carted off with an ankle injury during his NFL debut and finished without a catch. Tight end Jake Tonges also left the game on a cart after suffering an MCL knee injury, forcing NBC Sports to report that coach Kyle Shanahan said "it wasn't good."
San Francisco's receiving group was already thin before the game, missing Christian Kirk and Jordan Watkins. Now with Stribling sidelined and Tonges' status uncertain, the 49ers must lean more heavily on Mike Evans, Deebo Samuel, and Demarcus Robinson—who scored on a 39-yard touchdown catch. The injury clustering puts fresh pressure on quarterback Brock Purdy and what Yahoo Sports called a suddenly fragile depth chart.
De'Zhaun Stribling impressed during preseason with 11 catches for 109 yards in two games, raising expectations for his first NFL game. The injury struck early. Stribling limped to the medical tent during San Francisco's second drive, returned in the second quarter, then needed help leaving the field after contact with Rams cornerback Trent McDuffie. Fresno Bee reported he was carted off and ruled out for the remainder of the game.
Stribling switched from quarterback to wide receiver in seventh grade and played 56 games with 55 starts at Mississippi before graduating from Oklahoma State. His sudden exit leaves San Francisco with fewer young receiving options around Brock Purdy and forces the team to rely on veteran depth sooner than planned.
Jake Tonges had quietly become essential during George Kittle's absence. Over six games in 2025, Tonges caught 29 of 40 targets for 269 yards and three touchdowns—real production. He signed a two-year, $8 million contract that offseason, signaling the 49ers valued his work. His MCL injury against the Rams in Melbourne removes a player who had proven he could handle offensive responsibilities.
Coach Kyle Shanahan confirmed the injury is an MCL, not an ACL, but NBC Sports reported his assessment: "it wasn't good." Tonges was carted off the field, leaving the 49ers potentially dependent on just George Kittle and Luke Farrell at tight end. Losing a proven backup tight end concentrates workload and blocking assignments on fewer shoulders.
San Francisco entered the Australia game without Christian Kirk and Jordan Watkins. George Kittle was still ramping back from an Achilles injury. The roster was already walking a tightrope. Demarcus Robinson's 39-yard touchdown catch showed the team could move the ball, but it also revealed how much the 49ers now depend on a smaller group of healthy targets around quarterback Brock Purdy.
The 27-7 victory demonstrated the 49ers' system and quarterback play remain solid. But winning while losing Stribling and Tonges exposes a larger vulnerability: depth at receiver and tight end has evaporated. How long these injuries sideline both players will determine whether this season-opener win looks like a strong start or a hollow victory.
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