ENTOD Pharmaceuticals Secures Patent for Preclinical Topical Insulin Eye Drops to Aid Corneal Repair

ENTOD Pharmaceuticals has secured a patent for topical insulin eye drops being developed as a potential treatment to promote corneal cell growth, repair damaged tissue and possibly support corneal nerve health. The treatment remains in the pre-clinical stage, and additional laboratory and clinical studies are needed to establish its safety, effectiveness and appropriate uses. Researchers say the approach could offer a novel ophthalmic therapy with primarily local effects and limited impact on systemic blood-glucose levels, but its therapeutic value has not yet been proven. The company described the patent as evidence of India’s expanding capacity for original pharmaceutical research beyond generic drug production.
Dr. B. Vijaya Lakshmi said the research is notable because it explores insulin—an established biological molecule—through a completely different delivery route, potentially opening new avenues for ophthalmic research.
The topical insulin is being studied for specific corneal-repair effects, including encouraging corneal-cell growth, helping close damaged areas and protecting cells from injury.
ENTOD CEO Nikkhil K. Masurkar said the company aims to develop treatments “from India, for India, for the Global South, and ultimately for the world,” framing the project as part of a broader effort to build original pharmaceutical research capabilities.
The patent technology is described as the result of sustained research and development into new therapeutic pathways in ophthalmology, rather than a one-off discovery.
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