Mike Evans is a game-time decision for the 49ers facing Denver.

After Week 3, Shanahan said Evans had a rib injury—not an oblique injury—and that it “shouldn’t be long-term.” Trent Williams had a neck stinger and Dre Greenlaw a quad contusion; Shanahan said all three would need to be managed in practice.
If Evans is inactive, San Francisco’s healthy wide receivers on the active roster are Deebo Samuel, Brandin Cooks, Jacob Cowing and Jordan Watkins, according to the CBS report.
The 49ers entered the Cardinals game already without their top four receivers besides Evans, and had avoided putting some injured players on injured reserve partly to preserve their limited return-from-IR slots.
San Francisco had played its previous game without six of the 10 defensive linemen on its initial 53-man roster. Mykel Williams, who was on the physically unable to perform list, was set to open his practice window and could make his season debut in Week 5.
Star receiver Mike Evans is a game-time decision for the 49ers' Week 4 matchup against Denver after suffering a rib injury in San Francisco's Week 3 win over Arizona Durango Herald. Coach Kyle Shanahan said the injury "shouldn't be long-term," but Evans missed practice Wednesday and Thursday, leaving his status uncertain heading into Sunday NBC Bay Area.
The 49ers are battling a mounting injury crisis across their roster. Left tackle Trent Williams (neck stinger) and linebacker Dre Greenlaw (quad contusion) are also being managed carefully, while defensive end Nick Bosa is unlikely to play due to a calf injury San Luis Obispo. San Francisco has added veteran edge rusher Matthew Judon to the practice squad and brought back receiver Dante Pettis to shore up depth.
Though Evans sat out formal practice sessions midweek, he has been jogging on a side field, a positive sign for his availability NBC Bay Area. General manager John Lynch and Shanahan have expressed cautious optimism about his chances. The team is taking a day-to-day approach, hoping the injury won't sideline him long.
If Evans is inactive, San Francisco's healthy wide receivers on the active roster would be just Deebo Samuel, Brandin Cooks, Jacob Cowing, and Jordan Watkins San Luis Obispo. The 49ers entered last week's game already missing their top four receivers besides Evans, stretching the unit thin. Bringing back Pettis on the practice squad provides emergency depth but leaves limited experience ready to step in.
San Francisco played its last game without six of its original ten defensive linemen. Nick Bosa's calf injury keeps the star pass rusher sidelined, adding to losses across the line Mod Bee. The team is bringing back rookie Mykel Williams from the physically unable to perform list, who should open his practice window this week and could make his season debut in Week 5.
To bolster the edge rush, the 49ers signed veteran Matthew Judon to the practice squad, providing experienced depth. Romello Height is also expected to resume practicing soon, giving defensive coordinator options as injuries pile up Sacramento Bee.
Rather than place injured players on injured reserve, the 49ers have managed them day-to-day to preserve their limited return-from-IR slots for potential future needs San Luis Obispo. This strategy allows the team flexibility but forces them to be selective about which players get pushed through protocols. The approach hinges on Evans, Williams, and others either staying healthy or healing quickly enough to avoid longer absences.
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