Eli Lilly Breaks Ground on a $6.5 Billion Houston Facility to Produce Weight-Loss Drugs

State filings indicate the campus is planned to include at least six buildings totaling roughly 808,359 square feet, with construction expected to be completed in November 2027, although the plans remain subject to change.
Texas has offered Lilly $146 million in incentives through the Jobs, Energy, Technology and Innovation program, along with a $5.5 million grant from the Texas Enterprise Fund.
Gov. Greg Abbott called the project “the largest active pharmaceutical ingredient project in Texas history” and said the investment would reinforce Texas as “the global hub for life sciences.”
The Lilly project follows Bristol Myers Squibb’s announcement of a $2.3 billion, 600,000-square-foot manufacturing campus in Generation Park, strengthening the area’s emerging pharmaceutical cluster.
Generation Park developer McCord Development began positioning the 4,300-acre site for biotech companies 13 years ago and expanded its life-sciences education and workforce initiatives after losing Amgen’s planned $550 million biomanufacturing project in 2021.
Eli Lilly broke ground on a $6.5 billion manufacturing campus in Houston, marking chemical-manager the largest biotech investment in Texas history. The 236-acre facility in Generation Park will produce Foundayo, Lilly's newly approved oral GLP-1 drug for weight loss, along with other medicines and advanced therapies. Construction is expected to create roughly 4,000 jobs during building, with over 600 permanent positions once complete.
The Houston campus represents part of Lilly's larger $50 billion push to expand U.S. drug manufacturing. The company expects the facility to open in late 2027 and will seek regulatory approval for Foundayo in more than 40 countries, with international availability targeted for 2027.
State filings show the campus will include at least six buildings totaling roughly 808,359 square feet. Construction is projected to wrap up in November 2027, though plans remain subject to change. The site will house laboratories, manufacturing spaces, and offices for the 600-plus engineers, scientists, and technicians Lilly plans to hire.
Texas offered Lilly $146 million in incentives through the Jobs, Energy, Technology and Innovation program. The state also provided a $5.5 million grant from the Texas Enterprise Fund to help seal the deal. Governor Greg Abbott called the project "the largest active pharmaceutical ingredient project in Texas history" and said it reinforces Texas as "the global hub for life sciences."
Bristol Myers Squibb announced a $2.3 billion, 600,000-square-foot campus at the same Generation Park location. Together, the two investments signal a major shift in the site's purpose. Developer McCord Development spent 13 years positioning the 4,300-acre park for biotech companies, after losing Amgen's planned $550 million project in 2021.
Lilly committed $12.5 million to workforce training partnerships with San Jacinto College. The company also donated $2.5 million for student scholarships to help build a pipeline of workers for the new facility. These investments signal Lilly's long-term commitment to the Houston region and its growing life-sciences sector.
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