Louisville and Wake Forest Meet in Week 4 ACC Showdown Seeking Second Conference Win

Louisville hosts Wake Forest in a Week 4 ACC matchup, with both teams entering 2-1 and seeking a second conference win. The Cardinals are coming off a 41-31 victory over SMU and have averaged 46 points and more than 515 yards per game, led by quarterback Lincoln Kienholz and a productive rushing attack. Wake Forest, led by quarterback Gio Lopez, opened with wins over Akron and Purdue before losing 33-20 to Miami; its passing game has shown promise, though the Deacons struggled to run the ball against Miami. Louisville is favored by roughly 13 points at home, but previews note Wake Forest’s competitiveness against strong opponents and Louisville’s tendency to allow opponents to stay in games. Kickoff is scheduled for noon ET at L&N Federal Credit Union Stadium, with the game airing on ESPN.
Louisville defensive back Antonio Watts will miss the rest of the season with a knee injury, the university announced. Several other Cardinals, including starters Tre Richardson, Tayon Holloway and Koen Entringer, were listed as probable.
Louisville leads the all-time series 7-3. Its most recent meeting, in 2022, ended in a 48-21 Cardinals win after Louisville forced eight turnovers; Wake Forest had also won in Louisville in 2018, 56-35.
Louisville quarterback Lincoln Kienholz has completed 65.8% of his passes for 816 yards and six touchdowns in three games. Against SMU, he threw for 177 yards and two scores and added 42 rushing yards and a touchdown.
Wake Forest managed only 22 rushing yards, averaging 1.4 yards per carry, in its loss to Miami. In its earlier double-overtime win over Purdue, the Deacons rushed for 186 yards.
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