September 22 MLB Betting Markets Span Multiple Games

Christian Encarnacion-Strand has hit 10 home runs in 198 plate appearances this season, with a 45.0% hard-hit rate and a .350 wOBA. He has also posted a .413 wOBA and two homers over his last 35 plate appearances.
Trey Yesavage was scheduled to make his first start off the injured list, raising concerns about possible rust. FanDuel also noted that Encarnacion-Strand could face a Toronto bullpen with the 12th-worst reliever xFIP in the second half.
FanDuel explained that a +310 home-run prop implies roughly a 24% probability and would return $310 in profit on a $100 wager if the player homers.
FanDuel’s settlement policy says a home-run prop generally remains active if the player records at least one at-bat, including as a pinch hitter; the bet is typically voided only if the player does not appear at the plate.
MLB bettors looking to cash home-run props on September 22 should play it cautious. Chris Adkins warns that wind is blowing in at several parks, making long-ball wagers tougher than usual. Instead of stacking a risky seven-leg parlay, he recommends picking individual straight bets on hitters with the clearest edges against their scheduled pitchers.
FanDuel is highlighting Christian Encarnacion-Strand as a top home-run candidate against Toronto starter Trey Yesavage. The matchup has teeth: Encarnacion-Strand has crushed 10 homers in 198 plate appearances this year with a 45% hard-hit rate, while Yesavage returns from injury with a 4.56 SIERA and a fly-ball tendency that favors power hitters.
Chris Adkins targets Oneil Cruz to homer against Pirates right-hander Andre Pallante in an early game. Cruz mashes fastballs and has shown consistent pop against right-handed pitching. Pallante has served up homers at a rate that gives Cruz a clear edge. Adkins also likes Riley Greene against Washington, citing similar favorable matchups on the slate.
Encarnacion-Strand has been on fire lately. Over his last 35 plate appearances, he owns a .413 wOBA and two homers, showing the bat control and power FanDuel scouts look for. Yesavage's first start off the injured list raises rust concerns, and Toronto's bullpen ranks 12th-worst in reliever xFIP for the second half — meaning Encarnacion-Strand could face fatigue arms if the game stays tight.
A +310 home-run prop odds implies roughly a 24% win probability and returns $310 profit on a $100 bet if it hits. FanDuel sweetens the deal with its Daily Dinger promotion: if your pick homers, you get a profit-boost token for the next day's slate. Note that odds and eligibility shift daily, so lock in your bets early.
FanDuel settles home-run props generously. As long as a player records at least one at-bat — including as a pinch hitter — the bet stays active. The wager only voids if the player doesn't step to the plate at all. This rule gives bettors extra cushion on players who might see limited action.
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