Philadelphia Eagles Running Back Saquon Barkley Leaves Rams Game With Hamstring Injury

After being checked in the blue medical tent, Barkley was escorted to the Eagles’ locker room for further evaluation.
Barkley’s injury followed a run toward the sideline on which he went out of bounds to avoid a late hit; a Rams player dived toward his legs, though the article said the injury appeared to occur even without that contact.
The Eagles’ backup options include Tank Bigsby, who had taken on a substantial workload when Barkley previously left a game, and Will Shipley, whom the article described as a stronger pass-catching option for third downs.
The article noted Barkley had a hamstring injury in the 2018 preseason but missed no regular-season games with it, and reported no recorded hamstring strains since then; he did strain his groin in 2025.
Philadelphia Eagles running back Saquon Barkley left Sunday's game against the Los Angeles Rams in the first quarter with a right hamstring injury. USA Today reported that Barkley pulled up during a run, clutched his hamstring, and was escorted to the locker room for further evaluation. The team listed him as questionable to return.
The injury struck a blow to an Eagles offense already missing offensive tackle Lane Johnson and wide receiver DeVonta Smith. The New York Times noted that Barkley sustained the injury during a 6-yard run in the first quarter, leaving Philadelphia without one of its star playmakers.
Barkley went down during a run toward the sideline where he went out of bounds to avoid a late hit. Daily Mail reported that a Rams player dived toward his legs as the play unfolded. However, USA Today noted the injury appeared to occur even without contact, suggesting Barkley felt the hamstring pull on his own.
Philadelphia has depth options at running back to replace Barkley. Tank Bigsby took on substantial workload in a previous game when Barkley left the field. Clutch Points identified Will Shipley as a stronger pass-catching option for third downs, giving the Eagles flexibility in their running back rotation.
This hamstring injury marks a significant concern for Barkley's injury history. Yahoo Sports noted that Barkley had a hamstring injury in the 2018 preseason but missed no regular-season games with it. Since then, he reported no recorded hamstring strains until now, though he did suffer a groin strain in 2025.
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